Who We Are
The story of the company begins in 1993.
The then-manager opened ISOS International, headquartered in Ernster, Luxembourg, in a room of her house.
Initially, it was a sole proprietorship that harvested a few femoral heads in Luxembourg and Brussels, processed occasionally by Tutogen in Neunkirchen, Germany, using an organic solvent dehydration method known as Tutoplast®.
The business remained modest for over ten years.
Luc A. ALBY, who had long been collaborating with Tutogen in France, took an interest in this small entity, foreseeing a prosperous future, particularly due to Directive 2006/17/EC and the status it defined for allografts and their distribution across Europe.
He seized this opportunity to request, and subsequently obtained, a « tissue bank » license in 2007 from the Luxembourg Minister of Health.
Luc A. ALBY became a partner in the company and took over its management.

Simultaneously, he replaced Tutogen with other partners and expanded the supply to include human tissues from deceased donors in the United States and Korea, significantly diversifying the offerings and reducing costs.
This strategy of diversification and conquest of new markets continues.
ISOS was officially renamed Luxembourg Bone and Tissue Bank (LBTB).
Following the 2015 Directive, LBTB became an accredited Tissue Establishment at the European level.
The company today has 5 employees and remains the only private Tissue Establishment in the Grand Duchy of Luxembourg.
In 2021, LBTB partnered with Groupe Lépine, based in Genay, France. This synergy with its subsidiary, Tissue Bank of France (TBF) located in Mions, supported this acquisition. TBF, historically the first French tissue bank, devotes the majority of its resources to increasing its leadership in the domestic market, as well as to innovation and research.
Our History
How We Started

1993
Started Company
ISOS International

2007
Luc A. ALBY
became a partner in the company and took over its management.

2015
Establishment at the European level
LBTB became an accredited Tissue Establishment at the European level.

2021
Groupe Lépine
became the reference shareholder of LBTB.